Department of Biological Sciences, Crystallography,
University of London
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Normally lectures will be made available at the beginning of the week. Week numbers are sequential per term. Each TERM roughly coincides with a particular module. There will be deviations for a few individual lectures, in order to pace delivery of more difficult subjects. Some "weeks" in Terms 1 and 2 have a release which is intended to be studied over a 2-week period.
Official start date October 3rd.
Please complete enrolment including payment by Friday December 3rd. Closure date for applications Friday November 5th.
|TERM 1 (Module 1: Fundamentals of Protein Structure and X-ray Crystallography)|
|1-2||3-10||Introduction & Web Authoring||Overview of Protein Crystallography & General information (JMol, HTML, Images, IMS)||TEB|
|1-2||3-10||Protein Structure I||Primary Structure & Amino Acid and Peptide Bond Geometry||TEB|
|3||3-10||Protein Structure II||Non-Covalent (Non-Bonded) Interactions||TEB|
|4||17-10||Protein Structure III||Secondary Structure, Super Secondary Structure and Tertiary Structure||AB|
|5||24-10||Protein Structure IV||Quaternary Structure (Point Groups)||AB|
|6-7||31-11||X-Ray Diffraction I and the CCP4 Gui||Diffraction Theory (Scattering, Unit Cell, Braggs Law, Reciprocal Space, Indices, Structure Factor), using the CCP4 Gui and basic Fourier Theory||TEB|
|8||14-11||Symmetry I||Symmetry Operations (Rotational, Translational, Screw, Symbols, Unit Cell)||TEB|
|9-10||21-11||Symmetry II||Point Groups (Enantiomorphic, Polar, Laue Classes)||TEB|
|11||5-12||Protein Crystallography I||Protein Crystallisation||AB|
|12-13||9-1||Symmetry III||Space Groups (Enantiomorphic, Asymmetric Unit, P21, P212121)||TEB|
|14||23-1||Protein Crystallography II||X-Rays, X-Ray Sources (Laboratory, Synchrotron) & X-Ray Detectors (Image Plate, CCD).||AB|
|TERM 2 (Module 2: Protein Crystallography)|
|1||30-1||Protein Crystallography III||Data Collection (Oscillation Method) & Cryocrystallography||AB|
|2-3||6-2||Symmetry IV & Protein Crystallography IV||Extinctions, Space Group Determination & Data Processing||TEB|
|6||12-3||Protein Crystallography V||Molecular Replacement (Rotation Function, Translation Function), Patterson||TEB|
|7||19-3||Protein Crystallography VI||Isomorphous Replacement, Patterson||AB|
|8-9||23-4||Protein Crystallography VII||MAD, Anomalous Diffraction||ARC|
|10||7-5||Protein Crystallography VIII||Density Modification||TEB|
|11||14-5||Protein Crystallography IX||Electron Density Map, Modelling & Refinement||TEB|
|12||21-5||Protein Crystallography X||Validation & PDB||TEB|
|August 22nd||WRITTEN EXAMINATIONS|
|by Christmas||CERTIFICATES AWARDED|